A-286982
产品说明书
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同义名 : | - |
| CAS号 : | 280749-17-9 | |
| 货号 : | A1209591 | |
| 分子式 : | C24H27N3O4S | |
| 纯度 : | 97% | |
| 分子量 : | 453.55 | |
| MDL号 : | MFCD19690958 | |
| 存储条件： |
Pure form Inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | A-286982 is a potent and allosteric inhibitor of LFA-1/ICAM-1 interactions, with IC50s of 44 nM in the LFA-1/ICAM-1 binding assay and 35 nM in the LFA-1-mediated cell adhesion assay[1][2].A-286982 binds to the I structural domain allosteric site (IDAS), as evidenced by the fact that this isoform passes through the A-286982 binding site during delivery from the β-subunit I-like structural domain to the α-subunit ICAM binding site[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.20mL 0.44mL 0.22mL |
11.02mL 2.20mL 1.10mL |
22.05mL 4.41mL 2.20mL |
