tert-Butyl 11-aminoundecanoate

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Chemical Structure| 220851-29-6 同义名 : -
CAS号 : 220851-29-6
货号 : A1208523
分子式 : C15H31NO2
纯度 : 97%
分子量 : 257.41
MDL号 : MFCD31729305
存储条件：

Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Tert-Butyl 11-aminoundecanoate serves as a PROTAC linker with a PEG-based structure. It is utilized in crafting a range of PROTACs, which are compounds comprising two distinct ligands linked together; one binds to an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs leverage the cellular ubiquitin-proteasome system for the selective elimination of target proteins[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.88mL

0.78mL

0.39mL

19.42mL

3.88mL

1.94mL

38.85mL

7.77mL

3.88mL
参考文献

[1]Kim K, et al. Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci Rep. 2019 Dec 23;9(1):19654.