NSC 185058

产品说明书

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Chemical Structure| 39122-38-8 同义名 : -
CAS号 : 39122-38-8
货号 : A120064
分子式 : C11H9N3S
纯度 : 99%+
分子量 : 215.27
MDL号 : MFCD00448857
存储条件：

Pure form Keep in dark place, inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 NSC 185058 functions as an inhibitor of ATG4B, a prominent cysteine protease. The use of NSC 185058 to inhibit ATG4B significantly reduces autophagic activity [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.65mL

0.93mL

0.46mL

23.23mL

4.65mL

2.32mL

46.45mL

9.29mL

4.65mL
参考文献

[1]Huang T, et al. MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma. Cancer Cell. 2017 Dec 11;32(6):840-855.e8.