(E/Z)-Necrosulfonamide
产品说明书
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同义名 : | - |
| CAS号 : | 432531-71-0 | |
| 货号 : | A1191953 | |
| 分子式 : | C18H15N5O6S2 | |
| 纯度 : | 98%+ | |
| 分子量 : | 461.47 | |
| MDL号 : | MFCD02370191 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | (E/Z)-Necrosulfonamide, a racemic mixture of Necrosulfonamide, serves as an inhibitor of necroptosis by specifically targeting the mixed lineage kinase domain-like protein (MLKL). It hinders the MLKL-RIP1-RIP3 necrosome complex from engaging with downstream effectors. MLKL is deemed a vital target of RIP3 during necrosis initiation[1][2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.17mL 0.43mL 0.22mL |
10.83mL 2.17mL 1.08mL |
21.67mL 4.33mL 2.17mL |
