同义名 :	-
	CAS号 :	919783-22-5
	货号 :	A1188028
	分子式 :	C24H26N6O5
	纯度 :	99%+
	分子量 :	478.5
	MDL号 :	MFCD28386282
	存储条件：	Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	AZD1656 is a potent, selective, and orally active glucokinase activator, boasting an EC50 of 60 nM, with potential applications in type 2 diabetes research[1].[2].[3].

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.09mL 0.42mL 0.21mL	10.45mL 2.09mL 1.04mL	20.90mL 4.18mL 2.09mL

参考文献

[1]Brian E Ford, et al. Chronic glucokinase activator treatment activates liver Carbohydrate response element binding protein and improves hepatocyte ATP homeostasis during substrate challenge. Diabetes Obes Metab. 2020 Jun 10. [2]Medicinal Chemistry, et al. Design and Development of the Glucokinase Activator AZD1656. Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 1, 185-220. [3]Terri Mitchard, et al. The novel use of a heterozygous knockout mouse for embryofetal development assessment of a glucokinase activator. Birth Defects Res B Dev Reprod Toxicol. 2014 Apr;101(2):152-61.