MS402
产品说明书
 |
同义名 : | - |
| CAS号 : | 1672684-68-2 | |
| 货号 : | A1177083 | |
| 分子式 : | C20H19ClN2O3 | |
| 纯度 : | 99%+ | |
| 分子量 : | 370.83 | |
| MDL号 : | MFCD32067932 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | MS402 is a BD1-selective BET BrD inhibitor with Kis of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1), BRD2(BD2), and BRD2(BD2), respectively. MS402 prevents Th17 cell differentiation and ameliorates colitis in mice[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.70mL 0.54mL 0.27mL |
13.48mL 2.70mL 1.35mL |
26.97mL 5.39mL 2.70mL |
