SW-100
产品说明书
 |
同义名 : | - |
| CAS号 : | 2126744-35-0 | |
| 货号 : | A1177031 | |
| 分子式 : | C17H17ClN2O2 | |
| 纯度 : | 99%+ | |
| 分子量 : | 316.78 | |
| MDL号 : | MFCD32067911 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | SW-100 is a selective HDAC6 inhibitor with an IC50 of 2.3 nM and is at least 1000 times more selective for HDAC6 than all other HDAC isozymes. SW-100 has significant blood-brain barrier permeability[1].SW-100 significantly increases acetylated α-tubulin levels in a dose-dependent manner over a concentration range of less than 10 µM for 48 hours[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.16mL 0.63mL 0.32mL |
15.78mL 3.16mL 1.58mL |
31.57mL 6.31mL 3.16mL |
