AZD3229
产品说明书
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同义名 : | - |
| CAS号 : | 2248003-60-1 | |
| 货号 : | A1176920 | |
| 分子式 : | C24H26FN7O3 | |
| 纯度 : | 99.55% | |
| 分子量 : | 479.51 | |
| MDL号 : | MFCD31807612 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal mesenchymal tumours. c-KIT was inhibited by AZD3229 with an IC50 value of 223.3 nM[1][2].AZD3229 is a potent pan-KIT mutant inhibitor with potent growth inhibition (GI50=1-50 nM) in different mutant KIT-driven Ba/F3 cell lines[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.09mL 0.42mL 0.21mL |
10.43mL 2.09mL 1.04mL |
20.85mL 4.17mL 2.09mL |
