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同义名 : | VX-445 |
CAS号 : | 2216712-66-0 | |
货号 : | A1176769 | |
分子式 : | C26H34F3N7O4S | |
纯度 : | 99%+ | |
分子量 : | 597.65 | |
MDL号 : | MFCD32067875 | |
存储条件: |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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溶解度 : | - | |
动物实验配方: |
生物活性 | |||
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描述 | Elexacaftor is a modulator of CFT that promotes CFTR processing and trafficking, thereby increasing the amount of CFTR on the cell surface[1].Elexacaftor is a new generation CFTR modifier designed to restore the function of the Phe508del CFTR protein. Elexacaftor has potential for the treatment of cystic fibrosis[2]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.67mL 0.33mL 0.17mL |
8.37mL 1.67mL 0.84mL |
16.73mL 3.35mL 1.67mL |