DG-041
产品说明书
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同义名 : | - |
| CAS号 : | 861238-35-9 | |
| 货号 : | A1168303 | |
| 分子式 : | C23H15Cl4FN2O3S2 | |
| 纯度 : | 99% | |
| 分子量 : | 592.32 | |
| MDL号 : | MFCD18251534 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | DG-041 is a potent, high affinity and selective EP3 receptor antagonist with IC50s of 4.6 nM and 8.1 nM in binding and FLIPR assays, respectively. DG-041 inhibits the promotion of platelet aggregation by PGE2. DG-041 also crosses the blood-brain barrier[1][2].DG-041 has a weak antagonistic effect on DP1, EP1 and TP receptors with IC50 values of 131 nM, 486 nM and 742 nM, respectively[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.69mL 0.34mL 0.17mL |
8.44mL 1.69mL 0.84mL |
16.88mL 3.38mL 1.69mL |
