TCN 213
产品说明书
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同义名 : | - |
| CAS号 : | 556803-08-8 | |
| 货号 : | A1164152 | |
| 分子式 : | C18H24N4OS2 | |
| 纯度 : | 95% | |
| 分子量 : | 376.54 | |
| MDL号 : | MFCD04788042 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | TCN 213 is a selective, surmountable, glycine-dependent GluN1/GluN2A NMDAR antagonist with IC50s of 0.55, 3.5, and 40 μM in the presence of glycine at concentrations of 75 nM, 750 nM, and 7,500 nM, respectively.TCN 213 can be used to pharmacologically monitor changes in NMDAR expression in developing cortical neurons[1][2].At a concentration of 30 µM, TCN 213 antagonises NMDA-evoked currents in neurons transfected with the GluN2A subunit[1][2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.66mL 0.53mL 0.27mL |
13.28mL 2.66mL 1.33mL |
26.56mL 5.31mL 2.66mL |
