SC-57461A

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Chemical Structure| 423169-68-0 同义名 : -
CAS号 : 423169-68-0
货号 : A1163855
分子式 : C20H26ClNO3
纯度 : 99%+
分子量 : 363.88
MDL号 : MFCD00951253
存储条件:

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 SC-57461A is a potent, orally active, non-peptide selective inhibitor of LTA4 hydrolase with IC50s of 2.5 nM, 3 nM and 23 nM for recombinant human, mouse and rat LTA4 hydrolase, respectively[1].SC-57461A inhibits ionophore-stimulated LTB4 production in whole blood with IC50s of 49, 166 and 466 nM in human, mouse and rat, respectively[1] .
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.75mL

0.55mL

0.27mL

13.74mL

2.75mL

1.37mL

27.48mL

5.50mL

2.75mL