DMX-5804
产品说明书
 |
同义名 : | DMX-5084 |
| CAS号 : | 2306178-56-1 | |
| 货号 : | A1155036 | |
| 分子式 : | C21H19N3O3 | |
| 纯度 : | 99% | |
| 分子量 : | 361.39 | |
| MDL号 : | N/A | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor with an IC50 value of 3 nM and a pIC50 of 8.55 against human MAP4K4, and weakly against MINK1/MAP4K6 (pIC50, 8.18) and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances the cardiac function in mice. DMX-5804 increases the survival of mouse cardiomyocytes and attenuates ischaemia-reperfusion injury[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.77mL 0.55mL 0.28mL |
13.84mL 2.77mL 1.38mL |
27.67mL 5.53mL 2.77mL |
