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同义名 : | - |
CAS号 : | 1848242-58-9 | |
货号 : | A1155028 | |
分子式 : | C20H13ClF2N4O4S | |
纯度 : | 99%+ | |
分子量 : | 478.86 | |
MDL号 : | MFCD31813651 | |
存储条件: |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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溶解度 : | - | |
动物实验配方: |
生物活性 | |||
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靶点 |
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描述 | PI3K/mTOR Inhibitor-2 is a potent pan-PI3K/mTOR dual inhibitor with IC50 values of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. PI3K/mTOR Inhibitor-2 can inhibit p-AKT and p-p70s6k in MCF-7 cells, with IC50 values of 11.6 and 89.2 nM respectively[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.09mL 0.42mL 0.21mL |
10.44mL 2.09mL 1.04mL |
20.88mL 4.18mL 2.09mL |