Thalidomide-4-O-C2-NH2 HCl

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Chemical Structure| 2341840-99-9 同义名 : -
CAS号 : 2341840-99-9
货号 : A1148743
分子式 : C15H16ClN3O5
纯度 : 95%
分子量 : 353.76
MDL号 : MFCD32705128
存储条件：

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Thalidomide-4-O-C2-NH2 hydrochloride is a synthesized conjugate of an E3 ligase ligand and a linker, incorporating the Thalidomide-based cereblon ligand. It is utilized in PROTAC technology [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.83mL

0.57mL

0.28mL

14.13mL

2.83mL

1.41mL

28.27mL

5.65mL

2.83mL
参考文献

[1]Turk BE, et al. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production. Proc Natl Acad Sci U S A. 1996;93(15):7552‐7556.