RK-287107

产品说明书

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Chemical Structure| 2171386-10-8 同义名 : -
CAS号 : 2171386-10-8
货号 : A1145752
分子式 : C22H26F2N4O2
纯度 : 99%+
分子量 : 416.46
MDL号 : MFCD32062810
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 RK-287107, a powerful and selective tankyrase inhibitor, exhibits IC50 values of 14.3 nM for tankyrase-1 and 10.6 nM for tankyrase-2. It effectively halts the growth of colorectal cancer cells[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.40mL

0.48mL

0.24mL

12.01mL

2.40mL

1.20mL

24.01mL

4.80mL

2.40mL
参考文献

[1]Mizutani A, et al. RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model. Cancer Sci. 2018 Dec;109(12):4003-4014.