Piperonyl butoxide
产品说明书
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同义名 : | 胡椒基丁醚 ;ENT-14250; NSC 8401; ENT-142521 |
| CAS号 : | 51-03-6 | |
| 货号 : | A108763 | |
| 分子式 : | C19H30O5 | |
| 纯度 : | 95+% | |
| 分子量 : | 338.44 | |
| MDL号 : | MFCD00005842 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, room temperature In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Piperonyl butoxide is a semi-synthetic synergist for natural pyrethrum and synthetic pyrethroid insecticides in phytochemicals and biocides. Piperonyl butoxide is consequently a regular contaminant in stored grains, and subsequently in corresponding cereal food products and meat via feed uses[3]. Regarding multiple-T water maze performance at 10 weeks of age, no significant effect caused by PBO (Piperonyl Butoxide) treatment was observed. Exploratory behaviour examination of 8-week-old female mice indicated that the average speed declined in a significant dose-related manner, and the longitudinal pattern indicated a significant difference between the control and high-dose groups. For exploratory behaviour examination at 11 weeks of age, the total exploration distance shortened in a significant dose-related manner, and the average speed declined similarly. The PBO dose levels in this study produced several adverse effects on exploratory behaviour in female mice[4]. In addition, piperonyl butoxide activated c-Jun and ATF-2 in mouse hepatocytes during the early stage of hepatocarcinogenesis[5]. The inclusion of PBO along with emamectin significantly reduced resistant field populations of T. castaneum by at least 28% and the LC50 were lowered from 5.12 to 1.9 μg/ml with the highest synergism ration of 2.7 in resistant strain[6]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.95mL 0.59mL 0.30mL |
14.77mL 2.95mL 1.48mL |
29.55mL 5.91mL 2.95mL |
| 参考文献 |
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