生物活性 | |||
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描述 | Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA. It seems likely that the circulating substrates through which oral citicoline increases membrane phosphatide synthesis in the brains of humans involve uridine and choline, and not cytidine and choline as in rats[1]. Cytidine deamination from cytidine to uridine at immunoglobulin (Ig) gene loci is required for initiation of antibody diversification, while the same process also contributes to recurrent translocation or mutations outside of Ig loci in lymphocyte-origin tumors. Furthermore, genome sequencing of cancer cells from many tissue origins revealed a significant enrichment of cytidine deaminase mutagenesis signature in human cancers[2]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
4.11mL 0.82mL 0.41mL |
20.56mL 4.11mL 2.06mL |
41.12mL 8.22mL 4.11mL |
参考文献 |
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