Cytidine

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Chemical Structure| 65-46-3 同义名 : 胞苷 ;Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside; NSC 20258; β-D-Cytidine
CAS号 : 65-46-3
货号 : A107133
分子式 : C9H13N3O5
纯度 : 98%
分子量 : 243.22
MDL号 : MFCD00006545
存储条件:

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA. It seems likely that the circulating substrates through which oral citicoline increases membrane phosphatide synthesis in the brains of humans involve uridine and choline, and not cytidine and choline as in rats[1]. Cytidine deamination from cytidine to uridine at immunoglobulin (Ig) gene loci is required for initiation of antibody diversification, while the same process also contributes to recurrent translocation or mutations outside of Ig loci in lymphocyte-origin tumors. Furthermore, genome sequencing of cancer cells from many tissue origins revealed a significant enrichment of cytidine deaminase mutagenesis signature in human cancers[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.11mL

0.82mL

0.41mL

20.56mL

4.11mL

2.06mL

41.12mL

8.22mL

4.11mL

参考文献

[1]Wurtman RJ, Regan M, Ulus I, Yu L. Effect of oral CDP-choline on plasma choline and uridine levels in humans. Biochem Pharmacol. 2000;60(7):989-992

[2]Liu X, Meng FL. Generation of Genomic Alteration from Cytidine Deamination. Adv Exp Med Biol. 2018;1044:49-64