SIRT2/6-IN-1

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Chemical Structure| 1214468-35-5 同义名 : -
CAS号 : 1214468-35-5
货号 : A1070231
分子式 : C19H14N4O5S
纯度 : 95%
分子量 : 410.4
MDL号 : MFCD11667663
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 SIRT2/6-IN-1 inhibits SIRT6 and SIRT2, with IC50 values of 106 μM and 114 μM, respectively. It enhances H3K9 acetylation, boosts glucose uptake, and decreases TNF-α secretion in cells[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.44mL

0.49mL

0.24mL

12.18mL

2.44mL

1.22mL

24.37mL

4.87mL

2.44mL
参考文献

[1]Parenti MD, et al. Discovery of novel and selective SIRT6 inhibitors. J Med Chem. 2014 Jun 12;57(11):4796-804.