Olafertinib

产品说明书

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Chemical Structure| 1660963-42-7 同义名 : -
CAS号 : 1660963-42-7
货号 : A101185
分子式 : C29H28F2N6O2
纯度 : 97%
分子量 : 530.57
MDL号 : MFCD30345533
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Olafertinib, a third-generation inhibitor of EGFR TKI, demonstrates GI50 values at 5 nM for EGFR L858R/T790M, 10 nM for EGFR del19, and 689 nM for EGFR WT, indicating its research applicability in NSCLC[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.88mL

0.38mL

0.19mL

9.42mL

1.88mL

0.94mL

18.85mL

3.77mL

1.88mL
参考文献

[1]Misako Nagasaka, et al. Beyond osimertinib: The development of 3 rd-generation EGFR Tyrosine Kinase Inhibitors. J Thorac Oncol. 2020 Dec 15;S1556-0864(20)31105-9.