同义名 :	CID 664510
	CAS号 :	847163-28-4
	货号 :	A1002813
	分子式 :	C15H11N3O
	纯度 :	98%
	分子量 :	249.27
	MDL号 :	MFCD04183120
	存储条件：	Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	ML351 is a novel chemotype and the first reported selective inhibitor of 15-LOX-1 with IC50 value of 200 nM. It is a tight binding, mixed inhibitor which could protect against oxidative glutamate toxicity in mouse neuronal cells (HT-22) and significantly reduced infarct size in an in vivo mouse model for ischemic stroke.

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	4.01mL 0.80mL 0.40mL	20.06mL 4.01mL 2.01mL	40.12mL 8.02mL 4.01mL

参考文献
[1]Ganesha Rai, Netra Joshi, et al. Discovery of ML351, a Potent and Selective Inhibitor of Human 15-Lipoxygenase-1.