(E)-AG 99

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Chemical Structure| 122520-85-8 同义名 : AG 99; (E)-Tyrphostin AG 99; Tyrphostin AG-99; Tyrphostin 46; (E)-Tyrphostin 46
CAS号 : 122520-85-8
货号 : A1002383
分子式 : C10H8N2O3
纯度 : 99%+
分子量 : 204.18
MDL号 : MFCD00133901
存储条件:

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
靶点
  • EGFR/ErbB1

  • EGFR/ErbB1

  • EGFR/ErbB1

描述 (E)-AG 99, also known as (E)-Tyrphostin 46, is recognized as a strong inhibitor of EGFR. It actively inhibits the tyrosine phosphorylation of p145met and induces apoptosis, which is associated with the activation of caspase-like enzymes[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.90mL

0.98mL

0.49mL

24.49mL

4.90mL

2.45mL

48.98mL

9.80mL

4.90mL

参考文献