USL311

产品说明书

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Chemical Structure| 1373268-67-7 同义名 : -
CAS号 : 1373268-67-7
货号 : A1001764
分子式 : C24H34N6O
纯度 : 99%+
分子量 : 422.57
MDL号 : N/A
存储条件:

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Chemokines and chemokine receptors regulate multiple processes such as morphogenesis, angiogenesis and immune responses. Among the chemokine receptors, CXCR4 stands out for its pleiotropic roles as well as for its involvement in several pathological conditions, including immune diseases, viral infections and cancer[1]. USL311, a selective CXCR4 antagonist, exhibits an anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1) to CXCR4[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.37mL

0.47mL

0.24mL

11.83mL

2.37mL

1.18mL

23.66mL

4.73mL

2.37mL

参考文献

[1]Pozzobon T, Goldoni G, Viola A, Molon B. CXCR4 signaling in health and disease. Immunol Lett. 2016;177:6‐15

[2]Usl-311 for use in the treatment of cancer