DASA-58 is a selective activator of pyruvate kinase M2 (PKM2).

TEPP-46 is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2) with half-maximum activating concentration (AC50 value) of 92 nM, and has little or no effect on PKM1, PKL and PKR.

Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.

PKM2 Inhibitor is a pyruvate kinase M2 (PKM2) inhibitor with IC50 of 2.95 μM.