ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases.

SB-659032 is a selective and orally active inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) that is being developed for the treatment of atherosclerosis.

FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM) preventing PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis.

N-(p-amylcinnamoyl) Anthranilic Acid is a PLA2 inhibitor and TRP channel modulator.

Mepacrine 2HCl is an acridine-derived yellow dye, previously used in the therapy and prevention of malaria and later as an antiprotozoal and immunomodulatory agent. It's also an inhibitor of phospholipase A2.

Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 and 59 μM, respectively.

trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant.

U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO(5-lipoxygenase).

Aristolochic acid C, a metabolite of carcinogenic aristolochic acids (AAs). is a carcinogen found in aristolochia debilis. It can inhibit PLA2.

Difluprednate is a corticosteroid, approved difluprednate for the treatment of post-operative ocular inflammation and pain.