PDGFR

首页 / 抑制剂/激动剂 / / PDGFR

PDGFR 相关产品
PDGFR 亚型比较

全部(171) Inhibitor(27)

货号		产品名	纯度
A725907	现货	Ripretinib/瑞普替尼 DCC-2618 is a pan-KIT and PDGFRA inhibitor, and has antitumor activity.	99%
A135686	现货	Toceranib/托西尼布 Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.	96%
A431504	现货	SU4312 SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively), which is selective over EGFR and c-Src tyrosine kinases.	99%
A1280760	现货	Imatinib D4	99%
A1257150	现货	Telatinib mesylate	99%
A1216691	现货	Vorolanib Vorolanib (CM082) is an orally active, potent VEGFR/PDGFR/DHODH inhibitor.	99%
A546835	现货	Tyrosine kinase-IN-1 Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively.	99%
A929254	现货	TAK-593 TAK-593 is a potent and selective dual VEGFR/PDGFR inhibitor with IC50s of 3.2/0.95/1.1 nM (VEGFR1/2/3) and 4.3/1/13 nM (PDGFRα/PDGFRα V561D/PDGFRβ) and with an IC50 > 1 μM when tested against more than 200 protein and lipid kinases.	99%
A1210103	现货	N-(p-Coumaroyl) Serotonin	99%
A459806	现货	PD-089828	98%
A1461903	现货	Chiauranib	99%
A1554621	现货	PDGFR Tyrosine Kinase Inhibitor III	99%
A613718	现货	JNJ-10198409	99%
A1371593	现货	KG5	99%
A262997	现货	Methylnissolin/黄芪紫檀烷苷	99%
A561726	现货	AC710 AC710 is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM/1.0 nM/1.3 nM/1.0 nM for FLT3/KIT/PDGFRα/PDGFRβ respectively.	98%
A128191	现货	CGP-53716 CGP-53716 is a selective tyrosine kinase inhibitor of PDGFR.	98%
A1376658	现货	Seralutinib Seralutinib is a potent and novel inhaled PDGFR inhibitor, used in the study for pulmonary arterial hypertension.	99%
A243601	现货	Crenolanib/克莱拉尼 Crenolanib is a potent class III RTKs inhibitor with Kd values of 3.2nM, 2.1nM and 0.74nM for PDGFRα, PDGFRβ and FLT3.	99%
A422593	现货	Multi-kinase inhibitor 1	99%

产品名	PDGFR ↓ ↑	PDGFRα ↓ ↑	PDGFRβ ↓ ↑	其他靶点	纯度
Tyrphostin A9	+ PDGFR, IC50: 0.5 μM			EGFR	98%
Tyrphostin AG1296					99%+
Motesanib Diphosphate	++ PDGFR, IC50: 84 nM				99% (HPLC)
Pazopanib	++ PDGFR, IC50: 84 nM				99%
Imatinib	+ PDGFR, IC50: 100 nM			c-Kit	98%
Imatinib Mesylate	+ PDGFR, IC50: 100 nM			c-Kit	99%
Sennoside B	✔				99%+
PP121	++++ PDGFR, IC50: 2 nM			VEGFR,mTOR	99%+
Crenolanib		++++ PDGFRα, Kd: 2.1 nM	++++ PDGFRβ, Kd: 3.2 nM		99%+
Masitinib		+ PDGFRα, IC50: 540 nM	+ PDGFRβ, IC50: 800 nM		99%+
Ki8751		++ PDGFRα, IC50: 67 nM		c-Kit	99%
Tivozanib		++ PDGFRα, IC50: 40 nM	++ PDGFRβ, IC50: 49 nM		99%+
Ponatinib		++++ PDGFRα, IC50: 1.1 nM			98%
Amuvatinib		++ PDGFRα (V561D), IC50: 40 nM			99%+
Axitinib		+++ PDGFRα, IC50: 5.0 nM	++++ PDGFRβ, IC50: 1.6 nM		98%
CP-673451		+++ PDGFRα, IC50: 10 nM	++++ PDGFRβ, IC50: 1 nM		99%+
Telatinib		+++ PDGFRα, IC50: 15 nM		c-Kit	99%+
Nintedanib		++ PDGFRα, IC50: 59 nM	++ PDGFRβ, IC50: 65 nM		99+%
Avapritinib		++++ PDGFRα (D842V), IC50: 0.5 nM			99%+
MK-2461			+++ PDGFRβ, IC50: 22 nM		98%+
Lactate			+++ PDGFRβ, IC50: 27 nM	FLT3,c-Kit	85%
Linifanib			++ PDGFRβ, IC50: 66 nM		99%+
AZD2932			+++ PDGFRβ, IC50: 4 nM	c-Kit	99%
Dovitinib			+++ PDGFRβ, IC50: 27 nM	FLT3,c-Kit	99%+
Sorafenib			++ PDGFRβ, IC50: 57 nM mPDGFRβ, IC50: 57 nM		99%
Sunitinib			++++ PDGFRβ , IC50: 2 nM	FLT3	98%
Orantinib			+++ PDGFRβ, Ki: 8 nM		99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

PDGFR 亚型特异性产品

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z