PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and 18 nM) for human, rhesus and rat recombinant PDE9 respectively and high selectivity for PDE9 versus PDEs1-8 and 10-11.

PF-2545920 is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM, with > 1000-fold selectivity over the other PDEs.

5,7-Diacetoxy-8-methoxyflavone is a natural product isolated and purified from the roots of Scutellaria baicalensis.

Ayanin, a natural product isolated and purified from the rhizomes of Curcuma aromatica, with vasorelaxant activity and may have the potential for use in treating allergic asthma. Its IC(50) value 2.2mM for inhibiting interleukin (IL)-4 production from purified basophils.

HA130 is a selective ATX (autotaxin) inhibitor with IC50 of 28 nM.

VP3.15 Dihydrobromide is a novel dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor.