Fraxinol is a natural product isolated and purified from the bark of Fraxinus chinensis Roxb.

4,5-Dimethoxycanthin-6-one is a natural product isolated and purified from the barks of Picrasma quassioides (D.Don) Benn.

Polygalaxanthone III, a natural product isolated and purified from the roots of Polygala tenuifolia Willd., can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.

Humantenmine is a natural toxic compound isolated and purified from the roots of Gelsemium elegans with potential inhibition of several CYP450 enzyme activities.

Dihydromethysticin is one of the six major kavalactones found in the kava plant and has marked activity on the induction of CYP3A23.

Ezutromid is a small utrophin's translation modulator with EC50 of 0.4 μM .

Seneciphylline, a natural product isolated and purified from the herbs of Senecio scandens, can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduction of cytochrome P-450 and related monooxygenase activities.