Schizandrin is a natural product possessing antioxidant and anti-inflammatory activities.

Biricodar, a non-macrocyclic pipecolinate derivative, is multidrug resistance inhibitor.

Wilforine is a natural product isolated and purified from the vines of Tripterygium wilfordii, with insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system, and anti-inflammatory effect, which might be mediated by down-regulation of the expression of inflammatory factors TNF-α,IL-6 and NO.

Sinapine is an alkaloid from seeds of the cruciferous species which shows antioxidant and radio-protective activities and decreases expression of P-glycoprotein in Caco-2 cells.

HM30181 is a potent and selective inhibitor of P-glycoprotein.

Chonglou saponin VII, a natural product isolated and purified from the roots of Paris polyphylla, shows inhibitory effects on cell proliferation.

SC144 HCl is the first-in-class orally active small-molecule gp130 inhibitor (IC50 = 0.72 μM) which blocks cytokine-triggered gp130 signaling.

Elacridar is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules.

RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair.

Dofequidar is a quinoline compound, which can reverse P-glycoprotein (P-gp)-mediated MDR.

gp130-agonist-2 is a brain penetrant gp130 agonist which protects against NMDA-induced toxicity and increases STAT3 phosphorylation.

Tariquidar is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM, reverses drug resistance in MDR cell Lines.

Isosinensetin exhibits HIV-1 protease inhibiting and antioxidant activities. It is a natural product isolated and purified from the fruit of Citrus aurantium L..

Zosuquidar 3HCl is the 3HCl form of Zosuquidar. Zosuquidar is P-gp modulator that inhibited Pgp-ATPase activity 50-60% at 2 and 10μM and had no effect at 0.08 and 0.4μM.

Chrysosplenetin, a natural product isolated and purified from the herbs of Laggera pterodonta, is a metabolic inhibitor of artemisinin.