Rosavin, a natural product isolated and purified from the herb of Rhodiola rosea L. with anti-fatigue effect, decreases neovascular reaction on cutaneous angiogenesis induced in mice after grafting of syngeneic tumor cells.

Eugenol is a natural product used as a local antiseptic and anaesthetic. It is also used in perfumes, flavorings, and essential oils.

Betulin, a natural product isolated and purified from the barks of Betula alba L., is a sterol regulatory element-binding protein (SREBP) inhibitor withIC50value of 14.5 μM in K562 cell line.

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.

Theobromine, a xanthine alkaloid isolated and purified from the fruits of Theobroma cacao L., is widely consumed as stimulants and snacks in coffee and cocoa based foods and most often as part of ingredients in drugs.

Atomoxetine HCl is a phenoxy-3-propylamine-derived and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity.

Guanfacine HCl is a centrally acting antihypertensive with α2-adrenoceptor agonist with Kd value of 31 nM for α2A-adrenoceptor while displaying 60-fold selectivity over α2B-adrenoceptors, causing a decrease in heart rate and peripheral vascular resistance.

Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively.

Alfuzosin HCl is an antagonist of α1 adrenergic receptor used to treat benign prostatic hyperplasia (BPH).

Hemin is endogenously produced protoporphyrin IX containing a ferric iron.

Cyclobenzaprine HCl is a 5-HT2 receptor antagonist as a skeletal muscle relaxant and a central nervous system (CNS) depressant with elimination half-life of ‎32 hours.

Entacapone is a specific, potent and peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment.

Methoxsalen is a furanocoumarin and an active compound of a traditional Egyptian medicinal plant Ammi majus L, whose juice/fruit has been used for many years in folk phototherapy for the treatment of vitiligo or a hyperproliferative skin disorder, psoriasis. It is a potent suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight.

Iohexol is a non-ionic contrast agent used in myelography.

Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.