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PD 90780 is a non-peptide inhibitor of nerve growth factor (NGF) binding to p75NTR receptor. It inhibits NGF-p75 NTR interaction with IC50s values of 23.1 µM and 1.8 µM in PC12 cells and PC12 nnr5 cells, respectively.
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor with an IC50 of ~ 1 µM which inhibits NGF binding to p75NTR selectively over TRKA. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM.
Tags: NGF | 神经信号通路 | Neuronal Signaling | NGF 相关产品
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