KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10 nM for mTORC1 and mTORC2 respectively) with no effect on PI3Ks.

Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM exhibiting 1000-fold selectivity for mTOR than PI3K.

GSK2126458 is a highly selective and potent inhibitor of PI3K with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ, mTORC1/2 , respectively.

OSI-027 shows the selective and ATP competitive inhibition activities against mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively.

Palomid 529 is a novel dual mTORC1/2 inhibitor.

XL388 is a potent and selective ATP-competitive mTOR inhibitor with IC50 value of 9.9 nM.