Necrosulfonamide is a necroptosis inhibitor by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIP3).

TC13172 is a mixed lineage kinase domain-like protein (MLKL) inhibitor with an EC50 value of 2±0.6 nM for HT-29 cells.

Necrosulfonamide is a necroptosis inhibitor by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIP3).

GW806742X is an ATP mimetic MLKL inhibitor with Kd value of 9.3μM, and a VEGFR2 inhibitor with IC50 value of 2nM.