Spaglumic Acid is a neuropeptide found in millimolar concentrations in brain.

CPCCOEt is a hmGlu1 subtype-selective non-competitive antagonist with IC50 of 6.5 μM.

CPPHA is a selective positive allosteric modulator of mGluR5 receptor.

JNJ-46778212 is an mGlu5 positive allosteric modulator with an EC50 of 260 nM.

VU0422288, also known as ML 396, is a positive allosteric modulator (EC50 values are 108, 125 and 146 nM for mGlu4, mGlu8 and mGlu7 respectively).

(RS)-3-Hydroxyphenylglycine is a selective group I metabotropic glutamate receptor agonist.

FITM is a negative allosteric modulator of mGlu1 receptor with a Ki of 2.5 nM.

MNI 137 is a selective negative allosteric modulator of group II mGlu receptors.

MMPIP HCl is a 5-HT2C receptor antagonist.