Valbenazine is a prodrug of the(+)-α isomer of tetrabenazine for tardive syndrome therapy, and inhibits VMAT2 function.

Musk ketone, insoluble in water, can increase activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.

Tetrabenazine (+)- is a potent, selective and reversible VMAT-2 (vesicular monoamine transporter-2) inhibitor with Ki value of 100 nM.

AG-270 is a first-in-Class Oral MAT2A Inhibitor.

FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities[1].

AG-270 is a potent and orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with potential antineoplastic activity.

Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder.

Corticosterone is a steroid hormone produced in the cortex of the adrenal glands, which binds to and activates both glucocorticoid and mineralocorticoid receptors.

Reserpine is a naturally occuring brain-penetrant and irreversible VMAT (vesicular monoamine transporter 1 and 2) antagonist.