FLP 62064 is a potent 5-lipoxygenase (5-LOX) and COX-2 dual inhibitor. FLP 62064 has potently anti-inflammatory activity.

U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO(5-lipoxygenase).

Pectolinarigenin is a dimethoxyflavone extracted from the leaves of Linaria vulgaris Mill and it has been found to specifically bind to the nuclear receptor RARγ (IC50 = 3.42 μM) to activate the JNK signaling pathway and induce apoptosis.

BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL.

Silychristin, a natural product isolated and purified from the herbs of Silybum marianum (L.) Gaertn., is a plant growth regulator, an anti-hepatotoxic agent, and an inhibitor of horseradish peroxidases and lipoxygenase.

5-Hydroxy-3',4',7-trimethoxyflavone, a natural product isolated and purified fromt Lippia nodiflora L., shows prominent inhibitory activity against soybean lipoxygenase.

ML351 is a novel chemotype and the first reported selective inhibitor of 15-LOX-1 with IC50 value of 200 nM.