Silymarin, a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver cancer.

Dehydrodiisoeugenol, a natural product isolated and purified from the seeds of Myristica fragrans Houtt.

Eudesmin, a natural product isolated and purified from the dry leaves of Haplophyllum perforatum Kar.et Kir.

Pinoresinol, a natural product isolated and purified from the bark of Eucommia ulmoides Oliver, may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.

Sesamolin is a furofuran lignan extracted from sesame seeds, which has beneficial physiological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. It was also found to inhibit lipid peroxidation in rat liver and kidney.

Eleutheroside E, a principal component of Eleutherococcus enticosus, has anti-inflammatory and protective effects in ischemia heart.

Secoisolariciresinol, a natural product isolated and purified from the Heartwood of Podocarpus spicata, exerts a suppressive effect on the gain of body weight of mice fed a high-fat diet by inducing gene expression of adiponectin, resulting in the altered expression of various genes related to the synthesis and β-oxidation of fatty acids.

Paulownin, a natural product isolated and purified from the barks of Paulownia tomentosa, is active against the MCF-7 breast cancer cell line with IC50 values of 14.0 uM, and has the action of anti-inflammation, analgesia, immunity, hypoglycemia and has little toxicity.

Secoisolariciresinol diglucoside is an antagonist of platelet activating factor-receptor and used as an antioxidant.

Diphyllin, a natural arylnaphthalene, is potent inhibitor of vacuolar H(+)-ATPase (V-ATPase) that inhibits lysosomal acidification in osteoclasts.

Angeloylgomisin H, a natural product isolated and purified from the fruits of Schizandra chinensis, shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines and may present significant myocardial protective activity.

(±)-Galgravin is found in the flowers of magnolia biondii with anti-inflammatory and neuroprotective effects.

Picropodophyllotoxin is an orally active insulin-like growth factor-1 receptor (IGF-1R) inhibitor with IC50 of 1 nM, and exhibits little effect towards IR, FGFR, PDGFR and EGFR, and exerts no effects on microtubules and DNA topoisomerase II.

Phillygenin is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation .

4'-Demethylpodophyllotoxin shows potent cytotoxic potential in diverse cancer cell lines, it's a lignan isolated from the herb of Dysosma pleiantha (Hance) Woodson.