SP-600125 is a competitive and reversible JNK inhibitor with IC50 values of 40 nM, 40 nM and 90 nM for JNK1, 2 and 3.

Resveratrol is one of the numerous polyphenolic compounds found in several vegetal sources, has a wide spectrum of targets with IC50 of 0.8, 1, 3.3 and 5 μM for Adenylyl cyclase, IKKβ, DNA polymerase α and δ, respectively.

JNK-IN-8 is a potent, selective and irreversible JNK inhibitor with IC50 values of 4.7 nM, 18.7 nM and 1 nM for JNK1, 2 and 3, respectively.

JNK-IN-7 is a potent inhibitor for JNK all isoforms with IC50 values of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively.

Selective JNK inhibitor

JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively.

Triiodothyronine is a thyroid hormone generated by deiodination of the prohormone thyroxine (T4) and is a potent agonist of both thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both).

DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM, with less potency against JNK 1/2 with IC50 values of 390/360nM.

AS-602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.

BI-78D3 is a selective and competitive JNK inhibitor with IC50 of 280 nM.