AG-120 Racemate is the racemate form of AG-120 with no activity.

AGI-5198 is a potent and selective inhibitor of IDH1 R132H and R132C mutants with IC50 values of 0.07 and 0.16 µM, respectively, but not wild-type IDH1, wild-type IDH2, or IDH2 mutants.

Mutant IDH1-IN-2 is an inhibitor of mutant isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in fluorescence biochemical assay.

AGI-6780 is a selective inhibitor of IDH2/R140Q mutant with IC50 value of 23 nM,

BAY 1436032 is a potent, selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1).

Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM.

DS-1001b is a novel selective mutant IDH1 inhibitor with antitumor activity.

Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 μM.

Enasidenib mesylate is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes.

IDH-305 is a selective inhibitor of IDH1 R132H and R132C with IC50 of 18 and 28 nM, respectively.

Vorasidenib is an isocitrate dehydrogenase (IDH) inhibitor.

AG-120 is a first-in-class mutant IDH1 inhibitor.

Enasidenib is a selective mutant IDH2 enzyme inhibitor with IC50 of 12 nM.

D-alpha-Hydroxyglutaric Acid Disodium is a multiple-target inhibitor of KDM4A and α-Ketoglutarate(α-KG)-dependent dioxygenase, as well as an NF-κB activator.