Nelfinavir is a selective and potent HIV-1 protease inhibitor used in combination with other antiviral drugs in the treatment of HIV.

NHWD-870 is a potent and selective BET inhibitor that targets the bromodomains of BRD2/3/4 with IC50 values of 2.7nM, as well as BRDT.

Neoechinulin A, a natural product isolated and purified from Aspergillus chevalieri with anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits, and ameliorate rotenone toxicity by activating a cytoprotective machinery that requires ATP and antioxidant/anti-nitration activities.

Atazanavir Sulfate is a protease inhibitor used as an antiretroviral medication to treat and prevent HIV/AIDS.

Lopinavir is an antiretroviral of the protease inhibitor class, as well as an inhibitor of P-Glycoprotein, Cytochrome P450 3A and Organic Anion Transporting Polypeptide 1B1.

Saquinavir mesylate is an HIV Protease inhibitor used in antiretroviral therapy. Saquinavir could inhibit SARS-CoV-2 3CLpro main protease.

Darunavir is a protease inhibitor which acts on the HIV aspartyl protease.

Atazanavir is a protease inhibitor used as an antiretroviral medication to treat and prevent HIV/AIDS.

Fosamprenavir Calcium the prodrug of amprenavir which is an HIV protease inhibitor with antiviral property.

Amprenavir is a protease inhibitor used to treat HIV infection which can form an inhibitor-enzyme complex with HIV protease.

Nelfinavir Mesylate is a selective and potent HIV-1 protease inhibitor used in combination with other antiviral drugs in the treatment of HIV.

Tipranavir, a nonpeptidic HIV protease inhibitor (NPPI), inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-PI-resistant HIV-1 isolates.

Saquinavir is an HIV Protease inhibitor used in antiretroviral therapy. Saquinavir could inhibit SARS-CoV-2 3CLpro main protease.

Indinavir sulfate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.

Ritonavir is both an HIV protease inhibitor and a Cytochrome P450 3A inhibitor.

Escin IA is the main active ingredient of the saponin fraction of Aesculus chinensis Bunge fruits (SFAC) for the anti-TNBC metastasis activity, and its action mechanisms involved inhibition of EMT process by down-regulating LOXL2 expression.