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JIB-04 is a selective inhibitor of jumonji histone demethylase with IC50s of 230/340/855/445/435/1100, and 290 nM for JARID1A/JMJD2E/JMJD3/JMJD2A/JMJD2B/JMJD2C, and JMJD2D, respectively.
NCGC00244536 is a selective inhibitor of KDM4A with IC50 of 10 nM.
ML324 is an inhibitor of JMJD2 demethylase with IC50 of 920 nM with antiviral activity.
IOX1 is the broad-spectrum inhibitor of 2OG oxygenases and its IC50 for KDM4A/KDM3A and KDM4C/KDM6B/KDM2A/KDM4E are 0.6/0.1 μM and 0.6 μM/1.6 μM/1.8 μM/2.3 μM.
Tags: KDM4 | 组蛋白去甲基酶 | Histone Demethylase | KDM4 相关产品
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