PU-02 is an antagonist of serotonin (5-HT) receptor subtype 5-HT3.

Mequitazine is a potent, nonsedative and long-acting histamine H1 antagonist.

Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (Ki = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).

JNJ-39758979 is a selective, high-affinity histamine H4 receptor antagonist with Ki of 12.5 nM.

Diphenylpyraline HCl is a first-generation antihistamine with anticholinergic effects, acts as a dopamine reuptake inhibitor, shows to be useful in the treatment of Parkinsonism.

Chlorphenoxamine is an antihistamine and anticholinergic and can be used as antipruritic and antiparkinsonian agent.

Pitolisant HCl is an inverse agonist of human H3 receptor with Ki of 0.16 nM.

Hydroxyzine pamoate is a histamine H1-receptor antagonist.

VUF 10460 is a selective agonist of histamine H4 receptor with pKi of 8.22.

Bepotastine is a non-sedating and selective antagonist of the histamine 1 (H1) receptor.

2-Pyridylethylamine dihydrochloride is an agonist of histamine H1 receptor that produces vasoconstriction.

Azatadine dimaleate is an inhibitor of histamine and cholinergic with IC50 of 6.5 nM and 10 nM, respectively.

Epinastine is mast cell stabilizer and antihistamine that is used to treat allergic conjunctivitis.

Bavisant HCl is a highly selective, orally active antagonist of the human H3 receptor with a mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD.

Fexofenadine is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria.

Metiamide is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide.