Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV). It can be used to treat chronic HCV infection.

Glecaprevir is a NS 3/4A inhibitor potentially for the treatment of HCV.

Tegobuvir is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor.

R7128 is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes.

Ombitasvir is inhibitor of hepatitis C virus protein NS5A with EC50s of 0.82 pM to 19.3 pM against HCV genotypes 1 to 5.

AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV).

NM107 is an inhibitor of HCV RNA replication with IC50 of 7.0 μM.

Velpatasvir is an inhibitor of hepatitis C virus nonstructural protein 5A (NS5A) (genotype 1 (GT1) to GT6 replicons).

Mecarbinate is an anti-hepatitis C virus (HCV) agent.

Simeprevir is an inhibitor of HCV NS3/4A protease with Ki of 0.36 nM and EC50 of 7.8 nM against viral replication.

MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.

PF-4878691 is a potent and selective Toll-like receptor 7 (TLR7) agonist.

SB-9200 has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.

Clemizole HCl is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. The IC50 of Clemizole for RNA binding by NS4B is 24±1 nM, whereas its EC50 for viral replication is 8 µM.

ITX5061 is a type II inhibitor of p38 MAPK and also an antagonist of scavenger receptor B1 (SR-B1).