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货号 产品名 纯度
A1177198 现货 FLT3-IN-4

98%
A1902188 现货 PHI-101

99%
A1466435 现货 JI6

97%
A1176818 现货 FLT3-IN-3

99%
A188034 现货 MRX-2843

MRX-2843 is an orally available small-molecule inhibitor of both MERTK and FLT3.

99%
A1371593 现货 KG5

99%
A1249605 现货 3-Hydroxy Midostaurin

97%
A332881 现货 AI-10-49

AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 μM.

99%
A728069 现货 UNC2025 HCl

UNC2025 HCl is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.

99%
A845930 现货 Denfivontinib

G-749 is a FLT3 inhibitor that showed potent and sustained inhibition of the FLT3 wild type and mutants with IC50s of 0.4/0.6/3.5/7.5 nM for Wt Flt3/D835Y/MV4-11/Molm-14 respectively.

99%
A431319 现货 L-Pyroglutamic acid β-naphthylamide

98%
A321872 现货 UNC2025

UNC2025 is an inhibitor of Mer and Flt3 with IC50 of 0.8 nM and 0.74 nM, respectively.

99%
A715558 现货 FF-10101

FLT3-IN-1 is a potent FLT3 inhibitor extracted from patent WO2015056683A1, compound example A

98%
A929501 现货 5'-Fluoroindirubinoxime

5'-Fluoroindirubinoxime is an inhibitor of FMS-like receptor tyrosine kinase-3 (FLT3) with IC50 of 15 nM.

99%
A1671357 现货 AIMP2-DX2-IN-1

98%
A475775 现货 Quizartinib/奎扎替尼

Quizartinib is a second-generation FLT3 inhibitor for Flt3 (ITD/WT) with IC50 of 1.1 nM/4.2 nM, being 10-fold selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R.

99%
A1523464 现货 Tuspetinib

99%
A135706 现货 FLT3-IN-2

FLT3-IN-2 is a FLT3 inhibitor with IC50 of < 1 μM.

99%
A633839 现货 Fluorescein-5-maleimide/荧光素-5-马来酰亚胺

Fluorescein-5-maleimide is a fluorescent thiol-reactive dye used to conjugate fluorescein to proteins (excitation: 494 nm, emission: 519 nm).

99%
A1329297 现货 Fedratinib HCl hydrate

Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.

99%
产品名 FLT3 其他靶点 纯度
R406 Syk 98%
Go6976 99%+
Quizartinib +++

FLT3 (ITD), IC50: 1.1 nM

FLT3 (WT), IC50: 4.2 nM

98%
Gilteritinib ++++

FLT3, IC50: 0.29 nM

99%+
Amuvatinib +

FLT3 (D835Y), IC50: 81 nM

99%+
Pacritinib ++

FLT3 (D835Y), IC50: 6 nM

FLT3, IC50: 22 nM

97%
Dovitinib ++++

FLT3, IC50: 1 nM

c-Kit 99%+
Denfivontinib ++++

FLT3 (D835Y), IC50: 0.4 nM

FLT3, IC50: 0.4 nM

RET 99%+
TAK-659 HCl ++

FLT3, IC50: 4.6 nM

Syk 99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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