GS-441524, a small molecule nucleoside analog, strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection. It acts as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase.

GC376 is a 3CLpro (3C-like protease) inhibitor that shows promise in treating cats with certain presentations of FIP and has opened the door to targeted antiviral drug therapy.

CID 1375606 is an agonist of GPR27 (SREB1) that induces coupling of the receptor to β-arrestin 2.