Carperitide, also called as Atrial Natriuretic Peptide (ANP) (1-28), is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch.

Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

BQ-123 is a specific antagonist of endothelin A receptor (ETA) and the IC50 is 7.3 nM.

IRL-2500 is a potent endothelin receptor antagonist with IC50 values of 1.3 and 94 nM for ETB and ETA receptors respectively.

Atrasentan HCl is an endothelin receptor antagonist (IC50=0.0551 nM, ETA) being developed for the treatment of prostate cancer.

Atrasentan is an endothelin receptor antagonist (IC50=0.0551 nM, ETA) being developed for the treatment of prostate cancer.

Zibotentan is an orally administered, potent and specific ETA-receptor (endothelin A receptor) antagonist (IC50 = 21 nM).

Endothelin 1 (human, porcine) is a peptide vasoconstrictor and agonist of endothelin (ET) receptors ETA and ETB.

Ro 46-8443 is the first non-peptide Endothelin Receptor B selective antagonist with IC50 value of 110nM.

Ro 46-2005 is an antagonist of endothelin receptor.

BQ-788 sodium salt is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM.

ACT-132577 is the major and pharmacologically active metabolite of macitentan), which is dual ETA/ETB endothelin (ET) receptor antagonist designed for tissue targeting.

Ambrisentan is an oral, once-daily endothelin receptor antagonist that is selective for the endothelin type A receptor (IC50s = 0.251, 0.316, 0.398, 251, and 630 nM for rat preparations of heart, bladder, kidney, lung, and cerebral cortex, respectively).

Macitentan is an antagonist of endothelin receptor A (ETA) with IC50 of 0.5 nM. It is developed for treatment of pulmonary arterial hypertension (PAH).

Sulfisoxazole is an antagonist of endothelin receptor that can be used as a sulfonamide antibacterial agent.

Sodium ferulate is the sodium salt of ferulic acid which is used for the treatment of cardiovascular disease.

Bosentan is an endothelin (ET) receptor antagonist of ET-A (Ki = 4.7 nM) and ET-B (Ki = 95 nM).