MID-1 is a MG53-IRS-1 interaction disruptor. It abolished MG53-mediated IRS-1 ubiquitination and degradation, as well as sensitized insulin signaling and increased insulin-elicited glucose uptake with an elevated level of IRS-1 in C2C12 myotubes.

EMBL is an inhibitor of MuRF1.

NSC 697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E2) complex Ubc13-Uev1A.

TAK-243, also known as MLN7243 and AOB87172, is a small molecule inhibitor of ubiquitin-activating enzyme (UAE), with potential antineoplastic activity.

SMIP004 is an inducer of cancer-cell selective apoptosis of human prostate cancer cells, downregulates SKP2 and stabilizes p27.

C25-140 is an inhibitor of the TRAF6-Ubc13 interaction that reduces TRAF6-Ubc13 activity both in vitro and in cells.

TZ9 is an inhibitor of Rad6 ubiquitin conjugating enzyme (E2 enzyme) and inhibits MDA-MB-231 cell proliferation with IC50 of ~6 μM.

Thalidomide-O-amido-C4-Amine is a PROTAC block consist of Thalidomide linked to alkyl with Amine functional group for conjugation reactions.

Thalidomide-O-amido-PEG-C2-Amine is a PROTAC block consist of Thalidomide and a linker with Amine functional group for conjugation reactions.

Hinokiflavone, a natural product isolated and purified from the leaves of Platycladus orientalis, with significant cytotoxicity, can inhibit the activity of MMP-9.