Calicheamicin is a potent DNA crosslinker cytotoxic antibiotic.

PIP-199 is the most selective inhibitor of the RMI core complex/MM2 interaction.

Altretamine is an alkylating agent proposed as an antineoplastic.

Treosulfan is an alkylating agent used for conventional, as well as high-dose chemotherapy regimens, whereby plasma concentrations over 500 μg/mL can be achieved.

CB 1954 is an anticancer prodrug used in gene therapy research and is activated by NAD(P)H Quinone Oxidoreductase 2.

Lobaplatin is a diastereometric mixture of platinum(II) complexes containing a 1,2-bis(aminomethyl)cyclobutane stable ligand and lactic acid as the leaving group. Its antitumour activity results from the formation of DNA-drug adducts, mainly as GG and AG intra-strand cross-links.

Pipobroman is an anti-cancer drug that probably acts as an alkylating agent.

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

Nedaplatin is a derivative of cisplatin and DNA damage agent.

Bendamustine is a DNA cross-linking agent.

Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent.

Busulfan is a bifunctional alkylating agent.

Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism.

Thio-TEPA is an alkylating agent used to treat cancer, this molecule features tetrahedral phosphorus and is structurally akin to phosphate.