TC E3 5031 is a thalidomide derivate for conjugation reactions of PROTAC, which can hijack cereblon as the E3 ubiquitin ligase component.

TC E3 5032 is a thalidomide derivate for conjugation reactions of PROTAC, which can hijack cereblon as the E3 ubiquitin ligase component.

Thalidomide-O-C2-Amine HCl is a PROTAC block consist of Thalidomide linked to alkyl with an Amine functional group for conjugation reactions.

SY2-062 is a bromo substituted E3 Ligand for CRBN, structurally similar to Pomalidomide.

Pomalidomide can inhibit LPS-induced TNF-α release with IC50 of 13 nM in PBMCs.

E3 ligase Ligand 2 is a thalidomide derivate for conjugation reactions of PROTAC, which can hijack cereblon as the E3 ubiquitin ligase component.