Tetrahydropalmatine inhibits the LPSinduced production of COX-2 protein and mRNA in a dose-dependent manner.

(-)-Isocorypalmine, a natural product isolated and purified from the tubers of Corydalis yanhusuo W. T. Wang, with significant antifungal activity, also acts as a D1 partial agonist and a D2 antagonist to produce its in vivo effects and may be a promising agent for treatment of cocaine addiction.

Tetrahydrocoptisine is a natural alkaloid compound isolated and purified from Corydalis tubers with anti-inflammatory and anti-parasitic activities.

Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.

Scoulerine, a natural product isolated and purified from the herbs of Corydalis dubia., shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 ± 0.87 and 4.57 ± 0.42, respectively.

Dehydrocorydaline, a natural product isolated and purified from the tubers of Corydalis ambigua, inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.

Acetylcorynoline, a natural product isolated and purified from the tubers of Corydalis ambigua, has antifungal and anti-inflammatory activity.

Dihydroberberine, a natural product isolated and purified from the tubers of Corydalis decumbens (Thunb.) Pers., has anti-tumor activity. Dihydroberberine improves in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents, thus is potential therapeutic reagents for type 2 diabetes treatment.

Corypalmine, a natural product isolated and purified from the bulbs of Corydalis yanhusuo, inhibits prolyl oligopeptidase with IC50 of 128.0±10.5 uM, and shows inhibition activity against spore germination of some fungi.

(-)-Corydalmine exhibits antibacterial activities against staphylococcus aureus and methicillin-resistant S.

Corydine is found in tubers of corydalis tuberosa DC. with antimicrobial and antineoplastic activities. It can act as an adrenolytic and weak cholinergic agent.

Epiberberine chloride, a natural alkaloid, is a BACE1 inhibitor, which also exhibits inhibition activity on CYP2D6 and aldose reductase, alpha-adrenoceptors, acetylcholinesterase (AChE), butyrylcholinesterase, and b-site amyloid precursor protein cleaving enzyme 1.